🧠 Psychology · Biological Psychology

Neuroscience tricks that make the brain stick

Brain structures, neurotransmitters, and the nervous system β€” mastered.

🧬 Neuroscience

Memory tricks

Proven mnemonics — fast to learn, hard to forget.

Language Brain Areas
Broca's = speaking. Wernicke's = understanding.
Language Brain Areas
Two key language areas β€” and how to never mix them up
Broca's area (frontal lobe): speech production. Damage = Broca's aphasia β€” understands but can't produce fluent speech. Wernicke's area (temporal lobe): comprehension. Damage = fluent but nonsensical speech.
Broca's
Frontal lobe β€” speech production
Wernicke's
Temporal lobe β€” comprehension
Autonomic Nervous System
Sympathetic: Fight or Flight. Parasympathetic: Rest and Digest.
Autonomic Nervous System
Two branches of the ANS β€” opposites that keep each other in balance
Sympathetic: stress response β€” heart rate up, pupils dilate, blood to muscles. Parasympathetic: calm β€” heart rate down, digestion active, pupils constrict.
Sympathetic
Fight or flight β€” accelerates body
Parasympathetic
Rest and digest β€” calms and restores
Limbic System
Limbic system HHAC: Hippocampus, Hypothalamus, Amygdala, Cingulate
Limbic System
Four key structures that govern emotion and memory
Hippocampus: memory formation. Hypothalamus: hunger, thirst, temperature, hormones. Amygdala: fear and emotion. Cingulate cortex: attention and error detection.
H
Hippocampus β€” memory
H
Hypothalamus β€” homeostasis
A
Amygdala β€” fear/emotion
C
Cingulate β€” attention
Neuron Structure and Function
Neurons: dendrites receive, cell body integrates, axon transmits, synapse releases
Neuron Structure and Function
The basic unit of the nervous system β€” how a signal travels
Dendrites: receive signals from other neurons. Cell body (soma): integrates signals. Axon: transmits signal to terminals. Synapse: junction where neurotransmitters are released to the next neuron. All-or-nothing firing principle.
Brain Lobes and Functions
Brain lobes: Frontal (thinking, planning), Parietal (touch, spatial), Occipital (vision), Temporal (hearing, memory)
Brain Lobes and Functions
Four lobes of the cerebral cortex and what each does
Frontal lobe: executive functions β€” planning, decision-making, impulse control, working memory, motor cortex. Parietal lobe: somatosensory cortex (touch, pain, temperature), spatial awareness. Occipital lobe: visual processing. Temporal lobe: auditory processing, language (Wernicke's area), memory (hippocampus beneath).
Frontal
Planning, decision-making, motor control
Parietal
Touch, spatial processing
Occipital
Visual processing
Temporal
Hearing, language, memory
Key Neurotransmitters
Neurotransmitters: serotonin (mood), dopamine (reward), norepinephrine (arousal), GABA (inhibition), glutamate (excitation)
Key Neurotransmitters
Five neurotransmitters every psychology student must know
Serotonin: mood, sleep, appetite β€” low levels linked to depression. SSRIs block reuptake, increasing serotonin. Dopamine: reward, motivation, movement β€” excess linked to schizophrenia, deficiency to Parkinson's. Norepinephrine: arousal, fight-or-flight. GABA: main inhibitory NT β€” alcohol and benzodiazepines enhance it. Glutamate: main excitatory NT.
Serotonin
Mood, sleep β€” low = depression
Dopamine
Reward, movement
Norepinephrine
Arousal, stress response
GABA
Inhibitory β€” calms neural activity
Glutamate
Excitatory β€” activates neurons
Action Potential
Action potential: all-or-nothing. Resting potential: -70mV. Depolarization β†’ fires. Refractory period = brief pause.
Action Potential
How neurons fire β€” the all-or-nothing electrical signal
Resting: -70mV inside relative to outside (Na⁺ out, K⁺ in). Threshold: stimulus sufficient β†’ Na⁺ rushes in β†’ depolarization. Propagates down axon. Repolarization: K⁺ rushes out. Refractory period: brief inability to fire again. All-or-nothing: either fires fully or not at all β€” no partial signals.
Neuroplasticity
Neuroplasticity: brain reorganizes itself. Hebbian learning: neurons that fire together wire together.
Neuroplasticity
The brain's ability to change and reorganize throughout life
The brain is not static β€” it changes with experience. Hebbian learning: repeated activation of two neurons together strengthens their connection. London taxi drivers: enlarged hippocampus from spatial navigation demands. Stroke recovery: neighboring areas take over functions of damaged areas. Learning builds new synaptic connections.
Brain Lateralization
Hemispheric specialization: left (language, logic, detail). Right (spatial, holistic, creativity). Connected by corpus callosum.
Brain Lateralization
How the two hemispheres divide their functions
Left hemisphere: language (in most people), analytical thinking, detail processing, sequential. Right hemisphere: spatial processing, holistic thinking, face recognition, emotion processing. Contralateral control: left brain controls right side of body and vice versa. Corpus callosum: the bridge connecting hemispheres β€” severed in split-brain patients.
Endocrine System and Behavior
Endocrine system: hormones travel through blood. Slower than nervous system but longer-lasting effects.
Endocrine System and Behavior
How hormones influence psychology and behavior
Pituitary gland: 'master gland' β€” regulates other glands. Adrenal glands: cortisol (stress, immune suppression), adrenaline (fight-or-flight). Thyroid: metabolism and energy. Gonads: estrogen and testosterone β€” sexual development, mood, aggression. Pineal gland: melatonin β€” sleep-wake cycles.
Sleep Stages
Sleep stages: NREM 1-3 (light to deep sleep) β†’ REM (dreaming, memory consolidation). Cycle repeats ~90 min.
Sleep Stages
The sleep cycle and what each stage does
NREM Stage 1: light sleep, hypnic jerks. Stage 2: sleep spindles, K-complexes, consolidation begins. Stage 3 (slow-wave): deepest sleep, restoration, growth hormone release, hardest to wake. REM: rapid eye movement, vivid dreams, memory consolidation, muscle paralysis. ~4-5 cycles per night, REM lengthens toward morning.
Neurotransmitters
DASG-AEN β€” Dopamine, Acetylcholine, Serotonin, GABA, Acetylcholine, Endorphins, Norepinephrine
Seven major neurotransmitters and their primary functions
Each neurotransmitter has distinct functions β€” knowing which does what predicts drug effects
Dopamine: reward, motivation, motor control β€” low in Parkinson's, excess in schizophrenia. Serotonin: mood, sleep, appetite β€” low in depression, targeted by SSRIs. Norepinephrine: arousal, attention, fight-or-flight β€” targeted by SNRIs. GABA: main inhibitory neurotransmitter β€” low activity in anxiety; benzos enhance GABA. Glutamate: main excitatory neurotransmitter β€” involved in learning (LTP). Acetylcholine: memory, muscle movement β€” low in Alzheimer's. Endorphins: pain relief, euphoria β€” exercise "runner's high."
Dopamine
Reward and movement β€” Parkinson's and schizophrenia
Serotonin
Mood and sleep β€” SSRIs increase synaptic serotonin
GABA
Inhibitory β€” benzodiazepines enhance GABA activity
Brain Structures
HATCH β€” Hippocampus, Amygdala, Thalamus, Cerebellum, Hypothalamus
Five key subcortical structures and their primary functions
Know what each brain region does and what damage to it causes
Hippocampus: forming new explicit memories β€” damage causes anterograde amnesia (cannot form new memories). Amygdala: fear learning and emotional processing β€” hyperactive in anxiety disorders. Thalamus: sensory relay station (all senses except smell). Cerebellum: motor coordination and balance β€” damage causes ataxia. Hypothalamus: homeostasis (hunger, thirst, temperature, circadian rhythms), controls pituitary gland. Broca's area: speech production. Wernicke's area: language comprehension.
Hippocampus
New memory formation β€” damage = anterograde amnesia
Amygdala
Fear and emotion β€” hyperactive in PTSD and anxiety
Hypothalamus
Homeostasis and pituitary control β€” drives, hunger, thirst
Neural Communication
RDRA β€” Resting potential, Depolarization, Repolarization, Action potential
The sequence of events in neural firing β€” from resting state to action potential
Action potentials are all-or-none β€” the neuron either fires completely or not at all
Resting potential: -70mV β€” Na+ out, K+ in (sodium-potassium pump). Threshold: -55mV. Depolarization: Na+ rushes in β†’ membrane reaches +40mV. Repolarization: K+ rushes out β†’ returns to resting. Refractory period: absolute (cannot fire again), then relative (needs stronger stimulus). Action potential travels down axon β†’ triggers vesicle release β†’ neurotransmitters cross synapse β†’ bind receptors. Myelin sheath speeds conduction (saltatory conduction).
All-or-none
Neuron fires completely or not at all β€” no partial firing
Myelin
Speeds conduction β€” MS = myelin destruction
Synapse
NTs released into gap β†’ bind postsynaptic receptors
Hemispheric Specialization
LEFT = Language, Logic Β· RIGHT = Spatial, Creative
Lateralization of function between the left and right cerebral hemispheres
The two hemispheres specialize β€” split-brain research by Sperry and Gazzaniga proved it
Left hemisphere: language production and comprehension (in 95% of right-handers), analytical thinking, sequential processing, verbal memory. Right hemisphere: spatial processing, face recognition, holistic processing, emotional tone of speech (prosody), creative thinking. Corpus callosum: connects the hemispheres. Split-brain patients (corpus callosum severed): left hand "doesn't know" what right hand is doing β€” objects presented to left visual field (right hemisphere) cannot be named.
Left
Language, logic, sequential β€” dominant in most people
Right
Spatial, faces, holistic β€” prosody and creativity
Split-brain
Sperry and Gazzaniga β€” cutting corpus callosum separates hemispheres
🎓 Common Exam Questions
Q: Describe the steps of neural transmission from action potential to postsynaptic effect.
A: Resting potential: neuron at -70mV β€” maintained by Na+/K+ ATPase pump (3 Na+ out, 2 K+ in) and selective permeability. Stimulus reaches threshold (-55mV) β†’ voltage-gated Na+ channels open β†’ Na+ floods in β†’ depolarization to +40mV β†’ action potential. Repolarization: Na+ channels close, K+ channels open β†’ K+ flows out β†’ returns to resting. Absolute refractory period: cannot fire again (Na+ channels inactivated). Action potential travels down axon (myelinated = saltatory conduction, faster). At axon terminal: Ca2+ influx triggers vesicle fusion β†’ neurotransmitters released into synaptic cleft β†’ bind postsynaptic receptors β†’ excitatory (EPSP) or inhibitory (IPSP) postsynaptic potential. NT is then reuptaken, degraded, or diffuses away.
Q: What are the major lobes of the cerebral cortex and their primary functions?
A: Frontal lobe: motor cortex (voluntary movement), prefrontal cortex (executive function, planning, impulse control, personality), Broca's area (left hemisphere β€” speech production). Damage to PFC: personality change (Phineas Gage), impaired decision-making, loss of inhibition. Parietal lobe: somatosensory cortex (touch, proprioception), spatial processing, integration of sensory information. Temporal lobe: auditory cortex (hearing), Wernicke's area (left hemisphere β€” language comprehension), hippocampus and amygdala (deep), face recognition (right). Occipital lobe: primary visual cortex β€” destruction causes cortical blindness. Key principle: contralateral control β€” left hemisphere controls right side of body and vice versa.
Q: What is neuroplasticity and what are its implications for psychology?
A: Neuroplasticity: the brain's ability to change structure and function in response to experience throughout the lifespan. Mechanisms: synaptic strengthening (LTP β€” Long-Term Potentiation via NMDA receptors, Hebb's rule: neurons that fire together wire together), pruning (elimination of unused synapses β€” peaks in childhood and adolescence), neurogenesis (new neurons in hippocampus β€” promoted by exercise, stress-impaired). Implications: early experience shapes brain development profoundly β€” critical periods for language, vision, attachment. Recovery from brain injury possible through rehabilitation β€” undamaged areas take over function. Exercise promotes BDNF (brain-derived neurotrophic factor) and hippocampal neurogenesis. Depression associated with hippocampal shrinkage β€” antidepressants promote neurogenesis.
Q: How does the endocrine system interact with the brain to influence behavior?
A: Hypothalamic-Pituitary-Adrenal (HPA) axis: stress activates hypothalamus β†’ CRH β†’ anterior pituitary β†’ ACTH β†’ adrenal cortex β†’ cortisol. Cortisol: mobilizes energy, suppresses immune system, impairs hippocampal memory. Chronic stress β†’ hippocampal damage (dendritic retraction). Hypothalamic-Pituitary-Gonadal (HPG) axis: controls sex hormones (estrogen, testosterone). Testosterone: linked to aggression, dominance, and libido. Estrogen: mood effects, neuroprotective. Thyroid hormone: regulates metabolism β€” hypothyroidism causes depression-like symptoms. Oxytocin: bonding, trust, social recognition β€” released during touch and childbirth. Melatonin (pineal gland): circadian rhythm β€” light suppresses melatonin, darkness promotes it.
Q: Compare the sympathetic and parasympathetic divisions of the autonomic nervous system.
A: Sympathetic nervous system: 'fight or flight' β€” thoracolumbar (T1-L2). Increases heart rate, dilates pupils, diverts blood to muscles, inhibits digestion, stimulates epinephrine/norepinephrine release from adrenal medulla. Preganglionic: acetylcholine. Postganglionic: norepinephrine (most organs) or acetylcholine (sweat glands). Parasympathetic nervous system: 'rest and digest' β€” craniosacral (cranial nerves III, VII, IX, X + S2-S4). Decreases heart rate (vagus nerve), stimulates digestion, promotes sexual arousal, constricts pupils. Preganglionic and postganglionic: both acetylcholine. Enteric nervous system: 'second brain' β€” 100 million neurons in gut wall, operates independently. ANS controlled by hypothalamus. Biofeedback can train voluntary control of some ANS responses.